New ABFO Member Company Open Job Posting, Sr. Manager/Assoc Director/Director, Finance, Design Therapeutics


Position:  Sr. Manager/Assoc. Director/Director, Finance
Reporting to:  Vice President, Finance

Summary:  Design Therapeutics, Inc., preclinical-stage biopharmaceutical company pioneering novel small-molecule therapeutic candidates, called gene targeted chimeras (GeneTACs), that are designed to be disease modifying and target the underlying cause of inherited nucleotide repeat expansion diseases. Certain nucleotide repeat expansion diseases, such as Friedreich ataxia (FA), can result in reduced expression of specific mRNAs; in other diseases, such as myotonic dystrophy type-1 (DM1), Fuchs endothelial corneal dystrophy (FECD), and Huntington disease, the nucleotide repeat expansions result in the generation of toxic gene products, often associated with pathological nuclear foci. The Company’s GeneTACs are designed to selectively bind to genetic repeat sequences, modulate gene expression either by restoring or blocking mRNA transcription, and restore cellular health. The Company plans to initiate clinical trials with our lead product candidate in FA patients to evaluate its safety, pharmacokinetics (PK) and effect on FXN levels by the first half of 2022, and it expects to seek regulatory clearance for clinical trials in DM1 in 2023.

Job Description:  Working with the VP, Finance and Controller, the Sr Manager/Assoc. Director/Director of Finance will be responsible for certain finance and accounting activities of the organization to support the needs and requirements of a publicly traded company.  More specifically, the individual will lead the SEC compliance and reporting process, including internal controls and SOX compliance, technical accounting, the stock administration program, and internal reporting. The individual will also assist with the annual budgeting and periodic forecasting functions and lead the collaborative efforts on continual process improvements for its accounting and finance functions as the operations of the company grow, its needs and complexity increase and it continues to enhance its control environment.

Specific Duties and Responsibilities:

  • Manages the SEC reporting process (10Q/10K/Proxy) and related quarterly financial release materials to ensure compliance with SEC rules and regulations, compliance with U.S. GAAP and consistency across all communications.
  • Manages the internal controls over financial reporting (SOX) efforts, ensuring the company is properly mitigating financial risks while working to continuously improve its control environment in preparation for 404(b) compliance.
  • Manages the technical accounting function to ensure new, or newly relevant, guidance has been identified, properly accessed and documented in a clear, logical and comprehensive manner, and that the necessary controls and procedures are in place to allow for proper adoption.
  • Manages and maintains the stock administration system.
  • Continually seeks ways to improve operating efficiency within the department and overall business.
  • Prepares monthly budget vs. actual analysis for the executive team and department managers.
  • Support the general accounting function, including review and preparation of journal entries and account reconciliations, month-end analysis and overall general ledger maintenance.
  • Oversee the planning and coordination of audits and quarterly reviews; ensure timely and successful completion of financial audits.
  • Assists with the annual operating plan and monthly forecasting, meeting with department managers other key members, critically evaluating historical and forecasted spend.
  • Prepare and present materials to the Audit Committee.
  • Support system implementations and special projects as needed.

Essential Skills and Abilities:

  • Superior judgment and ability to demonstrate adaptability to individual needs while not compromising integrity and financial needs of organization.
  • Effective verbal and written communication skills, including the ability to document and translate complex financial transactions and effectively communication across all levels of the organization.
  • Strong interpersonal skills and ability to work effectively across all functions.
  • Excellent problem solving and analytical abilities.
  • Advanced Excel expertise, including financial modeling and analysis.
  • Effective organizational and problem-solving skills, including the ability to effectively manage multiple tasks.
  • Requires minimal supervision and ability to act independently.

Education and Experience Requirements:

  • Bachelor’s degree in Accounting or Finance
  • CPA required with deep knowledge of US GAAP
  • 7+ years of progressively responsible accounting or financial reporting experience; at least 2+ years of direct experience in each SEC reporting, financial planning and analysis and controllership roles
  • Previous public accounting experience
  • Previous experience at a publicly traded biotechnology company highly preferred

Association of Bioscience Financial Officers

Interested candidates please contact
Justin Thacker, Vice President, Finance at

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