New ABFO Member Company Open Job Posting, Senior Manager of Tax, Arrowhead Pharmaceuticals


Arrowhead Pharmaceuticals is a clinical stage, Nasdaq listed (ticker ARWR) company developing medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, our therapies trigger the RNA interference mechanism to induce rapid, deep and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specified gene, thereby affecting the production of a specific protein. Our RNAi-based therapeutics are at the leading edge with the potential to bring life changing treatments for patients.

Our Targeted RNAi Molecule (TRiMTM) platform utilizes ligand-mediated delivery and is designed to enable tissue-specific targeting while being structurally simple. The TRiM platform builds on more than a decade of work on targeted RNA delivery and offers several advantages including simplified manufacturing and reduced costs; multiple routes of administration; and potential for improved safety.

Our employees are nimble, science-driven, innovative professionals. A career at Arrowhead offers the opportunity to collaborate with top notch scientists to rapidly discover and develop RNAi-based therapeutics in a variety of indications to add to our growing pipeline.

Location:  Pasadena, CA

The Position:

Arrowhead seeks a Senior Manager of Tax to join its Finance and Accounting Team. This position will report into Arrowhead’s Director of Finance and Accounting.  This individual will be responsible for leading all aspects of corporate income tax, sales and use tax, real and personal property tax, and VAT and customs issues.  This individual will also be responsible for assisting the Director of Finance and Accounting in ad hoc Finance/Accounting projects.  The individual will work closely with members of the Finance and Accounting Team and will collaborate with many of Arrowhead’s operations departments. 


  • Corporate Income Tax:
    • Oversee, manage and review the Company’s third party tax consultants in preparing the Company’s income tax returns, tax provision for financial statement purposes, tax disclosures in SEC filings, and monitoring the company’s deferred tax assets and associated valuation allowance
    • Maintain and report on section 382 analysis, R&D tax credit and Orphan Drug tax credit opportunities
    • Lead tax-related special projects such as tax analysis and recommendations for business development transactions, intercompany transactions and contracts, creation of new legal entities, etc.
    • Support external auditor quarterly reviews and annual audits from a tax perspective
  • Other Tax Issues
    • Sales and Use Tax – prepare and ensure accuracy and timely completion of required state filings. 
    • International Tax Issues – research the appropriate positions for the Company on VAT issues and customs duties and ensure the accuracy of any filings as applicable.  Engage and manage third party specialists to assist as needed.
    • Real and Personal Property Taxes – research the appropriate positions for the Company on real and personal property tax issues and ensure the accuracy of any filings as applicable
    • Equity and Payroll Tax Issues – assist Payroll Manager and Director of Finance and Accounting in researching equity and payroll tax related issues as they arise
  • Assist Director of Finance and Accounting with other ad hoc SEC reporting and technical accounting issues
  • Participate in special Finance/Accounting projects


  • Bachelor’s degree in Tax, Finance or Accounting
  • Masters in Tax or CPA required
  • 10+ years of experience in progressively responsible and relevant tax, finance or accounting positions, preferably with commercial, public-company life sciences experience and a big 4 accounting firm
  • Strong understanding of federal, state and international corporate income taxation
  • Strong understanding of GAAP and SOX
  • Ability to gather, analyze and interpret information for completeness and accuracy; excellent attention to detail; excellent organizational skills;
  • Proficient in Microsoft Office suite (Excel – pivot tables, vlookups, etc.)
  • Strong communication skills (oral & written); ability to effectively interact with others at all levels – within and outside of finance
  • Demonstrated history of identifying problems, researching and recommending resolutions
  • Flexibility to put in extra hours during critical times such as month, quarter and year-end close cycles
  • Strong time management with the ability to work independently and in a group setting

Association of Bioscience Financial Officers

Please submit a resume and cover letter to

Arrowhead provides competitive salaries and an excellent benefit package.
All applicants must have authorization to work in the U.S. for a company.

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