Metacrine, Inc. is a clinical-stage biopharmaceutical company focused on building an innovative pipeline of best-in-class drugs to treat liver and gastrointestinal, or GI, diseases (



Job Description:

Reporting to the CFO, the Controller is responsible for managing financial risk, guiding decision making, building a robust financial infrastructure to support the needs of a publicly traded company and leading the SEC compliance, accounting and audit functions of the organization. The Controller ensures that financial policies are established and enforced; records are kept in a timely manner and in accordance with GAAP; adequate controls are in place to safeguard the organization’s assets and in accordance with SOX requirements and processes are established and enforced to ensure compliance with SEC and other regulatory requirements. The Controller leads collaborative efforts on continual process improvements.

Duties and Responsibilities:

  • Prepare SEC filings (10Q/10K) and related earnings release materials to ensure compliance with SEC rules and regulations, compliance with U.S. GAAP guidance and consistency across all communications
  • Lead complete effort among all functions within the company together with external resource to implement and monitor effectiveness of internal controls related to the financial reporting function to ensure compliance with Sarbanes-Oxley
  • Monitor and ensure timely identification of evolving accounting guidance and potential impact on the company; provide interpretation and document issues in a clear, logical and comprehensive manner
  • Lead and direct corporate tax compliance for annual returns, annual provisions as well as tax projects, as needed
  • Lead review of corporate contracts for accounting and tax implications
  • Lead training efforts across the organization around compliance with financial policies and regulatory matters
  • Set, oversee and adjust accounting department structure to optimize effectiveness and minimize risk
  • Review monthly financial statements including balance sheets, shareholder’s equity, and cash flow
  • Assess systems requirements for the accounting department in support of organizational growth; lead ERP and other accounting systems implementations
  • Lead and direct planning and coordination of audits and quarterly reviews; ensure timely and successful completion of financial audits
  • Direct and monitor compliance with internal controls related to financial policies to mitigate risk and engage in continuous improvement
  • Work with the CFO and audit committee to ensure compliance with audit committee charter
  • Prepare and present materials to the audit committee
  • Effectively manage accounting team including supervising direct report(s) by providing regular feedback, setting annual goals, completing regular performance feedback evaluations
  • Promote inclusive work environment for team and model inclusive behavior
  • Partner closely with all members of the senior management team on executing business strategies
  • Manage relationships with functional departments heads across the organization, staying abreast of strategic needs that may drive changes to financial policies, tools and risk management

Essential Skills and Abilities:

  • Superior judgment and ability to demonstrate adaptability to individual needs while not compromising integrity and financial needs of organization
  • Excellent management and supervisory skills
  • Effective verbal and written communication skills, including the ability to translate complex financial information
  • Strong interpersonal skills and ability to work effectively across all functions
  • Excellent problem solving and analytical abilities
  • Track record of assessing organization needs and implementing policies and procedures
  • Commitment to and experience in developing team skills and talents to meet the evolving needs of the organization

Education and Experience:

  • Bachelor’s degree in Accounting or related field
  • CPA required
  • 10+ years of progressively responsible accounting or financial reporting experience
  • Management experience required
  • Public company experience required
  • Public accounting experience with a Big 4 preferred


Interested candidates please reply to Trish Millican at

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