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COMPANY DESCRIPTION: NGM Biopharmaceuticals, Inc. is a biopharmaceutical company dedicated to discovering and developing the next generation of medicines for the treatment of serious diseases. Our experienced scientific team has joined forces with an impressive group of industry professionals, Nobel Laureates and other distinguished researchers to build a company where innovation and cutting-edge science has provided the foundation for a robust drug discovery engine. NGM’s current pipeline of clinical-stage programs consists of five drug candidates targeting liver and metabolic diseases, retinal diseases and cancer. The most advanced drug candidate, aldafermin (NGM282), is in Phase 2b clinical studies in non-alcoholic steatohepatitis (NASH) and is wholly-owned by NGM. Another drug candidate, NGM621, is in a Phase 2 study in geographic atrophy (GA) secondary to age-related macular degeneration (AMD). Over the past year we have also begun to unveil NGM’s oncology portfolio. In the fourth quarter of 2020, NGM announced two new oncology clinical candidates designed to broaden and deepen anti-tumor immune responses for patients with advanced solid tumors by reversing key myeloid and stromal resistance mechanisms. NGM707 is a novel dual antagonist antibody that inhibits Immunoglobulin-like transcript 2 (ILT2) and Immunoglobulin-like transcript 4 (ILT4). First-in-human testing for NGM707 is expected to begin in mid-2021. NGM438 is designed to inhibit LAIR1 interactions with stromal-derived collagens, and has the potential to block a stromal checkpoint and restore anti-tumor immune responses. NGM438 will enter the clinic at the end of 2021. Finally, NGM’s third oncology candidate is NGM120, a first-in-class antagonistic antibody that binds glial cell-derived neurotrophic factor receptor alpha-like (GFRAL) and inhibits growth differentiation factor 15 (GDF15) signaling. NGM120 is in an ongoing Phase 1a/1b trial in patients with cancer and cancer anorexia/cachexia syndrome (CACS). NGM’s has a strategic collaboration with Merck that began in 2015 and provides us with the resources and flexibility to pursue our ambitious R&D goals and further extend our pipeline of novel drug candidates. In exchange, Merck has a one-time option to license certain NGM pipeline programs – not including aldafermin or any programs returned to us by Merck – following human proof-of-concept trials under the terms of the companies’ ongoing strategic collaboration. Upon exercising any such option, Merck would lead global product development and commercialization for the resulting products, if approved. Prior to Merck initiating a Phase 3 study for a licensed program, NGM may elect to either receive milestone and royalty payments or to co-fund development and participate in a global cost and revenue share arrangement of up to 50%. The agreement also provides NGM with the option to participate in the co-promotion of any co-funded program in the United States. In January 2019, Merck exercised its first option under the collaboration to license MK-3655, previously referred to as NGM313. NGM Biosciences is looking for an experienced Chief Accounting Officer who will lead the company through a season of growth toward their mission of discovering and developing the next generation of medicines for the treatment of serious diseases. Reporting to the CFO, the Chief Accounting Officer will be responsible for the leadership, development, and execution of NGM’s accounting function including month-end and quarterly close operations, financial reporting, clinical trials accounting, SEC reporting, internal controls, 404B adoption, tax, stock administration and the development of world-class financial systems. Of critical importance will be this leader’s ability to establish credible working relationships with the company’s executive leadership team, functional leaders throughout the company, auditors and the Board of Directors. Responsibilities:
Requirements:
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Interested candidates can send their resume to Amy Hann Walker at amy@bvoh.com. To see this and other open financial positions with our ABFO member companies, To view this html email as a webpage in your browser, please use this link |
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